Lynda
Bellingham died from colon cancer - the fourth biggest cancer killer
worldwide, causing on average 694,000 deaths each year.
In countries such as the UK and U.S., more than 80 per cent of cases occur in people aged 60 or over, such as Lynda.
The
actress and TV presenter had been diagnosed with colon cancer a little
over a year ago. The disease later spread to her lungs and liver.
Despite knowing she may only have weeks to live, her death was quicker than many had expected.
Lynda, 66, was expecting to live until January 2015, and had planned to spend one last Christmas with her family.
Writing
in The Mail on Sunday last month, she said: ‘I would love to make one
more Christmas, if possible, but I want to stop taking chemo around
November in order to pass away by the end of January.’
Her
death came just days after she made an emotional return to TV show
Loose Women - where she used to be a panellist - for one final
appearance.
This morning, it was announced the much-loved actress and TV presenter died yesterday.
Her husband Michael was by her side in a London hospital.
Such a rapid decline is unusual, but not uncommon, oncologist Professor Karol Sikora told MailOnline.
He said: 'It's how most cancer patients want to die - where the final episode is very short.
He
explained there are many reasons why cancer patients die. Ultimately,
however, as the cancer grows, the burden becomes too much for the body.
'In the end, multi-system failure occurs - with vital organs such as the liver and kidneys slowing down and then packing up.
'No one knows exactly what causes it.'
He
added that different patients die at different stages of the disease.
This may be the differences in biochemistry, or sometimes, a will to
live.
'There are people who realise they aren't going to make it, just curl up and want to die.
'Then
there are those who are the opposite - they want to make it to their
daughter's wedding, make themselves live and die shortly afterwards.'
Lynda's
death came just days after the she made an emotional return to the TV
show Loose Women for one final appearance, where she appeared lively and
in good spirits
The spread of the cancer - known as metastasis - is very often what ends up killing patients.
Metastasis
is when cells from a tumour separate from it, find their way into the
lymph system or the bloodstream, and spread throughout the body.
Particular types of tumours often spread to particular organs. In bowel cancer patients, it tends to be the liver.
This
is because the main vein that drains the bowel goes to the liver,
explains Professor Sikora, founder of Cancer Partners UK.
This can disrupt the delicate balance of chemicals and salts in the body - with fatal consequences.
When cancer spreads to the lungs, there is eventually insufficient healthy tissue to absorb oxygen.
Cancer can block off part of the lung. This area may collapse and become infected, which can lead to death.
'However
it is possible there was a medical emergency,' he adds. 'The bowel may
have become obstructed - there could have been internal bleeding.'
Cancer
patients are also more likely to suffer from blood clots. If a clot
gets into the lung, for example, it can trigger a pulmonary embolism,
which can be fatal.
Lynda, with sons Michael, Robert, her step-son Bradley and husband
Michael, had wanted to spend one last Christmas with her family
Bowel cancer does also not respond as well to chemotherapy as some other cancers, such as breast, explained Professor Sikora.
This is because it very quickly becomes resistant to it.
Appearing
on ITV's This Morning two weeks ago, Lynda discussed how she had
planned to stop chemotherapy in November, due to the severe side effects
she had suffered.
She
said: 'There's no getting away from it with chemo - the ulcers in your
throat, the thrush, plus the fact I'd had major, life-saving surgery for
a perforated colon.
'When you're in terrible pain, you make decisions.'
She told hosts Phillip Schofield and Amanda Holden: 'I want my husband and children to see me off happy, contented.
'So I put the chemotherapy in a box.
'In this box, I could stop the chemotherapy after Christmas - I'm determined to hang on until Christmas.
'If my quality of life fades after that, I want to be able to open the box, make a choice and stop the chemotherapy.'
She said before this, she'd had no control over the decision - but had struggled with the idea of refusing treatment offered.
'I don't want to look ungrateful,' she explained.
'The box [decision] is there to be used if I need it.
'If my quality of life remains as it is now [after Christmas], then why would I hasten my death? '
Yesterday,
appearing on BBC Breakfast, she explained she had the option to resume
treatment if her health improves. 'It's there on the table if I want
it,' she said.
Lynda also admitted today there were times when she lay awake wondering about the future.
Speaking
about her new book, There's Something I've Been Dying To Tell you, she
said: 'The book is for everyone - every single day people are going
through this.
'As my oncologist says, the smallest cancer cell can outwit the brightest oncologist.'
In the piece she wrote for The Mail on Sunday last month, she described the devastating moment she was diagnosed.
'The
pleasant gentleman in front of me visibly crumpled. He stared at his
computer then seemed to pull himself up and looked me straight in the
eye.
‘"I
am so terribly sorry, I thought you had already been informed of your
position. You have cancer of the colon, and lesions on your lungs and
your liver".'
'I felt nothing except disbelief.'
The
actress said she had been ill the Christmas before and ended up in
A&E. 'I had been having really bad indigestion and then diarrhoea
quite badly, and I was short of breath.
'We
finally saw a doctor who said that it was probably nothing and to take
Omeprazole for a couple of weeks. I did, and everything seemed to clear
up.'
Months later, she was told there was a problem with a shadow on her liver - and see a colon specialist urgently.
She
wrote: 'The day finally came and those unforgettable words resounded
round the surgeon’s office – "Now about your cancer Miss Bellingham",
and, well, you know the rest by now.'
The actress said recently: 'As my oncologist says, the smallest cancer cell can outwit the brightest oncologist'
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